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Effect of Bromination on Quorum Sensing Inhibition of Indole Carboxaldehydes

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Quorum sensing is a form of bacterial communication that regulates group behaviors such as biofilm formation and production of virulence factors. As a result, inhibition of quorum sensing may prevent activation of pathogenesis in a number of bacterial species. Indoles are a type of signaling molecule found in many bacterial species and the indole derivative indole-3-carboxaldehyde has been found to inhibit quorum sensing mediated behaviors in Escherichia coli. Bromination may be a way to increase quorum sensing inhibiting properties of indole carboxaldehydes. The IC50s of three monobrominated indole carboxaldehydes were determined and compared to the IC50 of indole-3- carboxaldehye. IC50s of all three test compounds were significantly decreased from the control. There was not a significant difference between different bromination patterns, although two compounds showed a trend towards a reduced IC50 when compared to the third compound.


Prescription Boxes

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Type 2 diabetes is a disease that is chronic and difficult to manage that millions of Americans must learn to live with each day. Many people with type 2 diabetes have limited knowledge of the pathophysiology of the disease and factors that affect its progression. Guidance from healthcare in choosing the right diet and amount of exercise would be beneficial to improving the quality of life of patients living with this chronic disease. Education materials and opportunities are less effective in underserved populations due to factors such as the cost of transportation and fuel to clinics, the absence of Internet access to helpful educational websites, and the cost of food (Jessee & Rutledge, 2012). Communityinvolved clinics such as the Community Helping Place (CHP) Free Clinic in Dahlonega, GA have noticed this gap in knowledge and education and have implemented changes to benefit the population of underserved patients with diabetes in Dahlonega.

Faulknerian Social Strata Meridians in Yoknapatawpha County: A Study in Literary Geography

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William Faulkner may have claimed ownership of Yoknapatawpha County as a fictional destination whose inhabitants he had the exclusive right to mine for literary inspiration, but not even the sole proprietor and cartographer himself could have accounted for the transcendence of his literarily- and cartographically-delineated social stratums beyond the boundaries of his 2400-mile mythical county. Superimposed over a real map of Lafayette County, Mississippi, his birthplace and the very root of his modernist and Southern gothic canon, Yoknapatawpha is no more fictional than racism and gender inequality in the South. Faulkner’s maps themselves—of which there are two official copies, the first appearing in the back matter of the 1936 edition of Absalom, Absalom! and the second appearing in 1946’s The Portable Faulkner—have evolved over time to reflect the alterations of the land itself as it undergoes the shift into modernity. With the second, reduced printing in The Portable Faulkner, the map loses its nuance and much of Faulkner’s descriptions which lend meaning and depth to the maps, just as Yoknapatawpha and Jefferson do when their social strata begin to conglomerate. The maps, and the disparity between them, reveal a cartographical geography that plots the geospatial relationships between social classes in the post-Civil War South while upending the historical conceptions of these relationships.

Understanding the Student Perception of the Birth Process

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Nursing education is designed to prepare students to begin a career in healthcare, but the various methods of educating students can have a sharp impact on the student perception of critical physiologic processes. A majority of the information taught in nursing school requires students to hear the topic explained in a classroom setting and then receive hands on exposure to the subject in the clinical setting in order to gain a complete understanding of the material. The goal of nursing schools is currently to provide students with a variety of teaching styles in order to best prepare them to work in a hospital setting and be able to confidently provide holistic care. One of the focuses of nursing education is a brief introduction into the field of obstetric/maternity nursing. The phenomenon of childbirth is not easy to describe to a student with no knowledge or exposure to the birth process. This research was inspired by a desire to study what the experience of childbirth means to students in a nursing program. Focus will be given on analyzing how the nursing student population interprets and defines the complex process of labor and delivery based on their experiences with the event in their educational career.

How aspects of a modified Moore method in an upper-level, proof-intensive, collegiate mathematics course impact confidence among students

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In pursuing a degree in the field of mathematics, there comes a point when a student is no longer solving problems, but rather constructing mathematical proofs. It is through these proofs that we are able to verify the validity of different mathematical concepts and formulas. One must understand and be able to prove his work if he hopes to make his mark on the field. Further, the kind of thinking developed in this process is necessary for successful performance in a number of fields, especially science, technology, engineering and math (STEM). However, how does one learn the art of proof writing? A proof cannot be memorized and reproduced like the quadratic formula. A proof requires deep thought and planning in order to make the reader understand the logistics behind the argument. This process cannot be taught like a traditional algebra or calculus class. The best method for thoroughly and effectively teaching these classes is where research and opinions begin to differ among educators and mathematicians.

Therapeutic Effects of Bee Venom on Rheumatoid Arthritis

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Many beehive products such as propolis, Manuka honey, bee pollen, and royal jelly have been used by people due to their popular known health benefits. A novel bee product, bee venom, has demonstrated effective in treating various debilitating conditions, and thus bee venom therapy has been the subject of scientific studies to quantify its medical efficacy. Although bee venom has been used for millennia in Eastern medicine, modern bee venom therapy (BVT) originated in Europe in the 19th century, but was brought to the U.S. by Dr. Bodog Beck after World War I. The treatment became more widespread in the West as the 20th century progressed (Cooney et al, 2011). There are currently various application methods with the most popular being apipuncture (acupuncture with bee venom where needles are initially dipped into the venom before applied to the patient) and bee venom injections (Mohammadi et al, 2015). The multiple beneficial effects of bee venom include increased blood circulation, stimulation of the pituitary-cortical system, and reduced pain and inflammation (Mohammadi et al, 2015). These responses help treat the symptoms of many diseases and chronic inflammatory conditions. With additional research, the use of bee venom can be included as a means to safely alleviate the symptoms of several autoimmune diseases, especially rheumatoid arthritis (RA).

Sunburst

Is This All?

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Series Title: Snatched

Medium: Textiles

Dimensions: 34x56


I am a Nasty Woman

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Series Title: Snatched

Medium: Textiles

Dimensions: 34x56

Respect

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Series Title: Snatched

Medium: Textiles

Dimensions: 34x56

Stolen Innocence

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Series Title: Purity

Medium: Watercolor and ink on paper

Dimension: 28x30

Stolen Youth

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Series Title: Purity

Medium: Watercolor and ink on paper

Dimension: 28x30

Temptation

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Series Title: Purity

Medium: Watercolor and ink on paper

Dimension: 28x30

Guillibility

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Series Title: Purity

Medium: Watercolor and ink on paper

Dimension: 28x30

Gluttony

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Series Title: Purity

Medium: Watercolor and ink on paper

Dimension: 28x30


Densely Connected Convolutional Newal Networks for National Language Processing

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Densely connected convolutional neural networks are currently one of the best object recognition algorithms. Given the plasticity of neural networks, the DenseNet algorithm should perform similarly in NLP tasks. In its attempt to verify whether the DenseNet algorithm can yield equally impressive results on NLP tasks, this paper has modified the DenseNet algorithm and tested it on text classification. For this purpose, three differently sized datasets have each been encoded as Tf-IDf vectors and word vectors and then the DenseNet’s performance on these different feature sets was compared to more conventional methods including Naïve Bayes classifiers and other neural networks. The paper finds that DenseNets can perform on par with these algorithms but scale especially well with large datasets and semantically rich features.

Family Stories

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Electrocaoustic music has allowed for a profound development of narrative structures through a complex exploration of the human voice. From soundscapes exploring fragmented text in the work of Elainie Lillios to multi-level narratives such as in the work of Francis Dhomont, to new ‘instruments’ of vocal shards in Paul Lansky’s work, composers have teased and pulled at traditional vocal story-telling. I would like to explore some of these approaches to speech composition in the work FAMILY STORIES: SOPHIE, SALLY which was co-composed by Anna Rubin and Laurie Hollander, while reflecting on Lillios, Dhomont and Lansky’s approaches.

FAMILY STORIES is a text/sound piece using narrative, sampled ambient sounds and computer-generated music. Through a series of vignettes, it tells the story of a few years in the early life of Rubin's mother, Sophie Rubin, the child of Russian Jewish immigrants in Atlanta. Fragments of Yiddish, her mother tongue and klemzer music were part of her childhood memories of her early life. She was also deeply attached to an African-American woman, Sally Johnson, who took care of her after her mother became seriously ill But her mother’s death and the surviving family’s leaving Atlanta – without Sally Johnson – suddenly robbed her of both women who had nurtured her. The racism and anti-Semitism in early 20th century Atlanta are the atmosphere in this story of a child's unbearable loss The text was written by Rubin with help from actress/choreographer Aleta Hayes who portrays Sally Johnson in song and text within the piece.

Let the Darkness Out

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Catherine Likhuta’s music is emotionally charged, programmatic in nature, rhythmically complex, and demands the full control of the entire range of each instrument employed. While this is not a premiere, it is my belief that Let the Darkness Out (2011) is an important new work that has been added to the continually evolving repertoire of the 21st century and serves to strengthen the overall body of music heard at the conference. My performance/presentation will briefly discuss the jazz-influenced elements as well as the rhythmically complex and demanding aspects of this work and serve to introduce the audience to a general set of composer traits followed by a complete performance of the work.

Metric Structure of the compositions by Miles Okazaki

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American jazz guitarist/ composer and a professor the University of Michigan, Miles Okazaki released the revolutionary debut album Mirror in 2006, which he described as “my goal in writing the music for this album was to offer the listener a selection of rhythmic compositions that attempt to imitate the blending of formal order and organic beauty of form found in nature.” All of the music in this album owns a particular rhythmic concept as a structure of work, which is more like math and architecture along with a variety of musical styles such as Brazilian popular music, Indian, Middle-Eastern, African, classical and traditional/ contemporary jazz. In this paper, I will provide the analysis of the first track “Theme I” and the fourth track “Howl” from album Mirror which presents the best of Okazaki’s compositional style. These compositions exhibit how he utilizes rhythmic groupings, which sometimes shows a mirror/ symmetrical form over common meter as a metric structure of the piece to create a unique sound and feel. Since one part always keeps a repetitive rhythmic pattern expressing a common meter, music always produces a polyrhythmic feeling. “Howl” also features a metric modulation from 4/4 to 12/8 to 4/4 time signatures. I will also discuss how he adapts interesting melodic and harmonic structures on top of rhythmic structures, including the usage of a palindrome, pentatonic mode adaption over the augmented chord progression, slash chord, and a twelve-tone row.

Commissioning, Composing, and Conducting Contemporary Pedagogical Orchestra Music

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Over the past two years, the University of Oregon Campus Orchestra has commissioned and premiered four new works involving aleatoricism, graphic notation, atonality, and extended techniques. For many of the musicians in this ensemble, which is pedagogically based and open to students from all academic disciplines, these pieces were their first exposure to contemporary compositional techniques. It is essential to provide pedagogical ensembles with new works that both challenge and excite students about contemporary music. Numerous pedagogical advantages result from studying new work, including the focus on color and timbre, the experience of collaborating with a composer, and the expansion of the musicians’ definition of music.

In this presentation, we draw from our personal experiences conducting and composing for the UO Campus Orchestra to demonstrate the importance of creating a body of musically engaging contemporary works for pedagogical ensembles, and of introducing such works to these ensembles. We will focus on the collaborative process between conductor, composer, and ensemble, and the challenges faced when approaching this type of ensemble. To do so, we explore two of the pieces commissioned and performed by the UO Campus Orchestra: Cara Haxo’s Out of stone (2016), and Martín Quiroga’s A Quaint Snowfall (2016). We provide suggestions for both conductors and composers who are interested in incorporating contemporary techniques in hopes of encouraging more pedagogical ensembles to commission contemporary compositions. While this presentation is geared towards composing for orchestra, the concepts can easily be applied to the band, choir, chamber, and solo medium as well.

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